Aprotinin is a peptide protease inhibitor, derived from bovine lung tissue, capable of inhibiting a variety of proteases such as trypsin, chymotrypsin, and plasminase. Because of its powerful protease inhibition, aprotinin has been widely used in medical and biotechnology fields.

Function and advantage

Protease inhibition: Aprotinin can effectively inhibit the activity of a variety of proteases, preventing protein degradation and fibrinolysis.

Anti-inflammatory effect: By inhibiting proteases, aprotinin can reduce inflammation and protect tissues and organs from damage.

Anti-bleeding effect: Aprotinin reduces fibrin degradation by inhibiting fibrinolytic enzyme and has a significant hemostatic effect.

Application field

Surgery: Aprotinin is used in heart surgery and other major surgical procedures to reduce intraoperative bleeding and protect organ function.

Acute pancreatitis: Aprotinin is used to treat acute pancreatitis by inhibiting trypsin, reducing pancreatic inflammation and tissue damage.

Experimental studies: Aprotinin is used in molecular biology and biochemistry experiments to prevent the degradation of protein samples and protect the integrity of the samples.

Anti-inflammatory therapy: Aprotinin is used to treat various inflammation-related diseases by reducing proteinase-mediated tissue damage and reducing inflammatory responses.

Fibrinolytic inhibition: In certain blood disorders, aprotinin is used to inhibit fibrinolysis and help maintain normal blood clotting function.