The platform incorporates the latest advances in bioengineering, molecular biology and systems biology to comprehensively enhance the synthesis and productivity of microbial hosts. Through precise genetic manipulation and careful regulation of metabolic pathways, we are able to optimize the production process at the molecular level, resulting in a significant increase in the yield and quality of target molecules. In addition, our research platform focuses on the sustainability and cost-effectiveness of production, ensuring the economic viability of commercial production.
Key core technologies include:
(1) CRISPR-Cas9 gene editing technology: This technology allows us to perform high-precision gene spot editing, optimize the biosynthesis capacity of strains, and increase the production rate of specific active molecules.
(2) Metabolic pathway Engineering: By designing and reconstructing key biochemical pathways, we improve the throughput and efficiency of pathways and optimize the transformation from simple precursors to complex high-value products.
(3) Synthetic biology circuit design: advanced design, construction and verification methods are adopted to integrate artificial gene networks to achieve precise control of cell behavior.
(4) High-throughput screening technology: combining automated and computational biology tools to rapidly evaluate and select strains with optimal production characteristics.
(5) Flow cytometry and mass spectrometry: Using these high-end analytical technologies, we are able to monitor the entire production process in real time to ensure product quality and process stability.
The integration of these technologies has not only improved our.
Genetic and metabolic engineering research platform